The only problem with the OEM injectors is that with a tune they are pretty much at their limit of being able to deliver fuel. So with an E85 tune, which will use more fuel than regular fuel because E85 contains less energy per unit than regular fuel, you have to upgrade your injectors.
If you're not going E85 then the OEM injectors are probably ok, but as you get up there in airflow you do not have any wiggle room for fueling, which is why I put in the 42 lb injectors. There are lots of tables where the ECM will enrich the mixture, such as cat overtemp protection, if IAT gets over 80* it enriches the mixture, again at 100*, and there's more. Sooo, if you push your IDC to the limit and the ECM tries to add more fuel and can't, that could potentially be a problem.