What kind of mileage do you have on your spark plugs. Sounds like misfire. Trifecta tune/ high boost will slowly degrade your plug gap. Start by checking your plugs and making sure they are at .028"
I used to (about a year ago) occasionally get that code. It seemed to only happen on hot days with the A/C on when I was getting on the freeway full steam after work.
I cleared it each time. Changed nothing else, found no problems and it hasn't been back since.
Obviously, inspect for boost leaks. But if you clear it and it doesn't come back often, I wouldn't worry too much.